According to Ed Grabianowski at io9, (not just him obviously) humans have survived near extinctions before.
Now, of course, every school child knows it was the first proto-zombie outbreak.There is one near-extinction event that is fairly well-known, although it remains controversial. Roughly 70,000 years ago, give or take a few thousand years, an enormous eruption occurred in what is now Sumatra, leaving behind Lake Toba (the crater lake pictured above). The eruption coincides with a population bottleneck that is often cited as the reason for the relatively low genetic diversity across Homo sapiens sapiens. Research suggests as few as 2,000 humans were left alive by the eruption and its aftereffects.
I think Ink is making a bad thing 1000x worse. Remember, people in the Colony had never seen a behemoth before. The zoms they knew were bad but unorganized. They tended to do random crowd movement type runs. Assuming that Ink isn't one of a cadre with members all over the world--we don't know what's going on everywhere.
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