Quote Originally Posted by UndeadSweeper View Post
Could it be compare to being in a coma state, where you are aware of everything that around but unable to move or said anything?
Not quite, in a coma as they are thus far understood, the patient is unconscious and without discernible brain function. In the case of depersonalization, the person suffering is "awake" but may feel like they are in a dreamlike state and like they are watching themselves as an observer, rather than a participant in the actions they are taking.

Another seemingly related affliction is Locked in Syndrome. This is where the person suffering has lost all voluntary motor control, yet retains all of their higher brain function. LIS can be simulated with Curare poisoning, which when I followed that down the wiki hole, led me to D-tubocurarine, yet another complex carbon ring molecule.

Following on the click throughs, I was also led to Akinetic Mutism. This is a mental state where the sufferer exhibits symptoms that mirror those of LIS, but to a lesser degree. It has been described as "lacking the will to move." Many cases of AM are caused by a stroke originating in the Thalamus, the region of the brain I was trying to remember above. The thalamus is described as being the "central switchboard" and a relay between subcortical areas and the cerebral cortex. Zombification changes in the brain are probably most evident and/or centered here... "...the only test is an autopsy."