Witch_Doctor: Any thoughts on where those variants originated from? Let's not forget the runners and jumpers, and even TOWTM who DO seem to be previously human.

Of the ones that dont appear human (D.A.H.), is it a combination of zedism and the third agent or the third agent alone that creates these creatures?

Perhaps the third agent changes the original infection vector and TOWTM has figured out a way to utilize that?