I don't think Hope is going to die - or if she does, it'll be a tragic accident rather than by biter. Hope is no Tommy. I think Hope and Datu's relationship is already pretty clear - she's the one thing he cares about most, I agree. This may manifest itself later, but I don't think it'll play out to be that important per se. I do think that even if most major characters end up dying in Season 4, Hope and Datu will live. Or maybe they'll die together. I agree that their fates are bound together. Datu has already suffered greatly by losing Samantha, to make him lose Hope too is just... unnecessarily cruel, and not really in keeping with the show's themes. What would be more likely is if Hope was kidnapped or some such that Datu would do unspeakable acts to help her, ala Kalani/Hannah, and what was hinted at with the Saul/Lizzie thing.