Neither the zombies (regular or irregular) nor the Mallers/Colony are a good enough reason for nuking that part of the country. And ground zero can't be where it started because Kimmet said that it started in the East.
Vast majority of human race is either dead or apart of the creatures/zombies/whatever the fuck you want to call them. Even if every concentration of them was nuked off the face of the earth they would still greatly outnumber the living.
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